Antibacterial Effects of Streptococcus Salivarius K12 on Oral Bacteria
문윤미, 문정은, 이미라, 조자원,
소속 상세정보
문윤미 ( Moon Yun-Mi ) - Seonam University Department of Dental Hygiene
문정은 ( Moon Jung-Eun ) - Dankook University Graduate School Department of Oral Health
이미라 ( Lee Mi-Ra ) - Baekseok University Department of Dental Hygiene
조자원 ( Cho Ja-Won ) - Dankook University College of Dentistry Department of Preventive Dentistry
KMID : 1157520160120040209
Abstract
Objective: For the purpose of this study is to study the antibacterial effects of probiotics S. salivarius K12 on oral bacteria (Aggregatibacter actinomycetemcomitans, Actinomyces naeslundii, Enterococcus faecalis, Fusobacterium nucleatum, Porphyromonas endodontalis, Porphyromonas gingivalis, Streptococcus gordonii, Streptococcus mutans).
Methods: The antimicrobial activity of eight oral bacteria and S. salivarius K12 tests were performed. S. salivarius K12 culture medium and A. actinomycetemcomitans, A. naeslundii, E. feacalis, F. nucleatum, P. endodontalis, P. gingivalis, S. gordonii S. mutans culture alone turbid liquid and mixed, and then the incubator at 37oC in anaerobic conditions and cultured 36 hours. The oral bacteria and S. salivarius K12 using a phase contrast microscope, and the state was observed with bacterial contamination, using a spectrophotometer was an antibacterial test.
Results: S. salivarius K12 showed antibacterial effects proportional to the injection amount increase for above certain concentrations on Actinobacillus atinomycetemcomitans, Actinomyces naeslundii, Enterococcus faecalis, pophyromonas gingivalis, Streptococcus Streptococcus mutans. S. salivarius K12 increased the growth of germs in a condition of low concentration of Fusobaterium nucleatum, pophyromonas endodontalis, but showed antibacterial effects proportional to the injection amount increase for above certain concentrations.
Conclusion: Based on the experiment results of probiotics S. salivarius K12 on the oral bacteria causing oral cavity, S. salivarius K12 showed antibiosis against oral bacteria when it remains inside the mouth for above certain concentrations. Accordingly, it is thought that it would be effective to use S. salivarius K12 as a clinical method of preventing oral cavity.
키워드
probiotics; bacteria; streptococcus salivarius
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